PrimaVie

Research / Clinicals | References

Please see below for additional information on PrimaVie® Shilajit.

JOURNAL ARTICLES & STUDIES

Alam, M., et al. "Studies on Authentic Shilajit Samples." B.M.E.B.R IV (1979): 54-61.

Alam, M., et al. Chemical Examination of Commercial Gomuthra. 525-529.

Bhattacharyya, Sauryya. et al. "Beneficial Effect of Processed Shilajit on Swimming Exercise Induced Impaired Energy Status of Mice." Pharmacologyonline 1: 817-825 (2009).

Bhattacharyya, Sauryya. et al. "Shilajit Dibenzo-a-Pyrones: Mitochondria Targeted Antioxidants." Pharmacologyonline 2: 690-698 (2009).

Bhattacharya, S. K. "Shilajit Attenuates Streptozotocin Induced Diabetes Mellitus and Decrease in Pancreatic Islet Superoxide Dismutase Activity in Rats." Phytotherapy Research 9(1995):41-44.

Bhattacharya, S K., Bhattacharya,A., and Ghosal, S. "Anxiogenic Activity of Methylenedioxymethamphetamine (Ecstasy): an Experimental Study." Biogenic Amines 14 (1998): 217-237.

Bhattcharya, S.K., and Ghosal, S. "Effect of Shilajit on Rat Brain Monoamines." Phytotherapy Research 6(1992): 163-164.

Bhaumik, S., Chattopadhyay,S., and Ghosal, S. "Effect of Shilajit on Mouse Peritoneal Macrophages." Phytotherapy Research 7 (1993): 425-427.

Bucci, L.R. "Selected Herbals and Human Exercise Performance." American Journal of Clinical Nutrition 72 (2000): 624-636. www.ajcn.org.

Chauhan, S. Accelerated Stability Study of Purified Shilajit Extract. Comp. Sudhakar Agrawal. Indian Herbs Research & Supply Co. Ltd. 2000. 1-5.

Cianci, M., Rizkallah,P.J., Olczak,A., Raftery,J., Chayen, N.E.,. Zagalsky, P.F., and Helliwell, J.R. "The Molecular Basis of the Coloration Mechanism in Lobster Shell." PNAS 99 (2002): 9795-9800. www.pnas.org.

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Ghosal, S. Muruganandam,A.V., and Chauhan, S. The Marine Origin of Shilajit. R&D Centre, Indian Herbs Ltd.

Ghosal, S. The Facts and Facets of Shilajit. In: Research and Development of Indigenous drugs: Inst.of History of Medicine and Research, New Delhi,1989: 72-80.

Ghosal, S., Reddy,J.P., and Lal, V.K. "Shilajit I: Chemical Constituents." Journal of Pharmaceutical Sciences 65 (1976):772-773.

Ghosal, S.,. Kanikkannan,N and. Ramarao, P. "Shilajit- Induced Potentiation of the Hypoglycemic Action of Insulin and Inhibition of Streptozotocin Induced Diabetes in Rat. " Phytotherapy Research 9(1995):66-68.

Ghosal, S, and. Bhattacharya, S.K.. "Antioxidant Defense by Native and Processed Shilajit - a Comparative Study." Indian Journal of Chemistry 35B (1996): 127-132.

Ghosal, S, and Singh,S. "Anti-Ulcerogenic Activity of Fulvic Acids and 4'-Methoxy-6-Carbomethoxybiphenyl Isolated From Shilajit." Phytotherapy Research 2 (1988):187-191.

Ghosal, S, Mukhopadhyay,B., and Bhattacharya, S.K. "Shilajit: a Rasayan (Immunomodulator) of Indian Traditional Medicine". In : Molecular Aspects of Asian Medicines, Ch XI, eds.Mori, A. and Saton, PJD Publications Ltd.,Westbury,2001:425-444.

Ghosal, S, et al. "Mast Cell Protecting Effects of Shilajit and Its Constituents." Phytotherapy Research 3 (1989): 249-252.

Ghosal, S., et al. "Shilajit. Part 4. Chemistry of Two Bioactive Benzopyrone Metabolites." J. Chem Research (S) (1989): 350-351.

Ghosal, S, et al. "Similarities in the Core Structures of Shilajit and Soil Humus." Soil Biol. Biochem 25 (1993): 377-381.

Ghosal, S, et al. "The Need for Formulation of Shilajit by Its Isolated Active Constituents." Phytotherapy Research 5 (1991): 211-216.

Ghosal, S., Lal,J., and Singh, S.K. "The Core Structure of Shilajit Humus." Soil Biol. Biochem 23 (1991): 673-680.

Ghosal, S, Kawanishi,K and Saiki,K. "The Chemistry of Shilajit Odour." Indian Journal of Chemistry 34B (1995): 40-44.

Ghosal, S., Baumik,S., and Chattopadhyay, S . "Shilajit Induced Morphometric and Functional Changes in Mouse Peritoneal Macrophages." Phytotherapy Research 7(1993): 425-427.

Ghosal, S., Singh, S.K.,and Srivastava, R.,. "Shilajit. Part 2. Biphenyl Metabolites From Trifolium repens." J. Chem. Research (S) (1988): 196-197.

Ghosal, S. "Ayuryedic Maharasas, the Repository of Primordial Organic Chemistry." J. Indian Chem. Soc. 74 (1997): 930-936.

Ghosal, S. "Chemistry of Shilajit, an Immunomodulatory Ayurvedic Rasayan." Pure & Appl. Chem. 62 (1990): 1285-1288.

Ghosal, S. "Shilajit Odour: Its Origin and Chemical Character." Indian Chem. Soc. 71 (1994):360-364.

Ghosal, S. "Shilajit: Its Origin and Significance." Indian J. Indg. Med. 9 (1992):1-2.

Ghosal, S. "The Saga of Shilajit."Plenary Lecture, Proceeding of 2nd Indo-Korean Symposium on Natural Products,Seoul, Korea,1992:10-12.

Ghosal, S. Dibenzo-a-Pyrone Chromoproteins (DCPs) - the Major Bioactive Compounds of Shilajit. PCT Application/US2005/008577.

Ghosal, S. Composition of Stable Bioactive Metabolites of DHA and EPA-WO/2006/007310.

Ghosal, S. Further Information on the Bioactives of Shilajit. Drug Research & Development Centre. 2001. 1-4.

Ghosal, S. Impact of Pro-/Anti-Oxidant Activity of Shilajit, FUSOM and Dibenzo-a-Pyrone in Presence of Ferric Ion. 1-2.

Ghosal, S. "Shilajit: Its Origin and Vital Significance".In: Traditional Medicine, ed.by B.Mukherjee, Oxford-IBH, New Delhi,1993: 308-319.

Ghosh, A. Conjugated Protein of Bioastin and Velvet Antler Vis-a-Vis Shilajit Protein. Comp. Ghosal,S. Drug Research & Development Centre. 2002. 1-18.

Ghosh, A. Isolation & Separation of Low & Medium Molecular Weight Compounds From Shilajit (as Per New Protocol Given by Prof. S. Ghosal). Comp. Ghosal,S. Drug Research & Development Centre. 2002. 19-25.

Ghosh,. A. Isolation and Characterization of Active Chemical Compounds from Planktons. Comp. Ghosal, S. Drug Research & Development Centre. 2001.

Ghosh,. A. Isolation and Characterization of FUSOMS from Shilajit. Comp. Ghosal, S. Drug Research & Development Centre. 2000. 45-51.

Ghosh,. A. Shilajit Proteins (SP). Comp. Ghosal,S. Drug Research & Development Centre. 2002. 1-34.

Ghosh,. A., and. Ghosal, S. Pro-Oxidant Activity of Native Shilajit, FUSOM and Dibenzo-a-Pyrone (DBP) by Reduction of DPPH Radical. Drug Research & Development Centre. 1999. 1-9.

Ghosh, A. Shialjit Fusom. Drug Research & Development Centre. 2001.

Goel, R.K., and Sairam, K. "Anti-Ulcer Drugs From Indigenous Sources with Emphasis on Musa sapientum, Tamrabhasma, Asparagus racemosus and Zingiber officinale." Indian Journal of Pharmacology 34 (2002): 100-110.

Goel, R.K., Banerjee, R.S., and Acharya, S.B.. "Antiulcerogenic and Antiinflammatory Studies with Shilajit." Journal of Ethnopharmacology 29 (1990): 95-103.

Hagen, T., et al. "Feeding Acetyl-L-Carnitine and Lipoic Acod to Rats Significantly Improves Metabolic Function While Decreasing Oxidative Stress." PNAS 99 (2002): 1870-1875. www.pnas.org.

Halliwell, B, and Whiteman, M. "Measuring Reactive Species and Oxidative Damage in Vivo and in Cell Culture: How Should You Do It and What Do the Results Mean?" Britsh Journal of Pharmacology 142 (2004): 231-255. www.nature.com.

Jaiswal, A.K., and BhattcharyaS.K. "Effects of Shilajit on Memory, Anxiety, and Brain Monoamines in Rats." Phytotherapy Research 6(1992)163-164.

Kong, Y.C., et. al. "Chemical Studies on a Nepalese Panacea- Shilajit (I)." International Crude Drug Res. 25 (1987): 179-182.

Kumar, V. LD50 Study of Purified Shilajit. Indian Herbs Research & Supply Co. Ltd. 2001. 1-2.

Kumar,. V. LD50 Study of Raw Shilajit. Comp. Das, S.N. Indian Herbs Research & Supply Co. Ltd. 2003. 1-2.

Kumar, V. Report on Sub-Acute Toxicity Study of Purified Shilajit. Comp. Das, S.N. Indian Herbs Research & Supply Co. Ltd. 2001. 1-12.

Lederer, E. "Chemistry and Biochemistry of Some Mammalian Secretions and Excretions." J.Chem.Soc. (London)(1949): 2115-2125.

Lee, H, S.A. Kizito, et. al. "Analysis of Headspace Volatile and Oxidized Volatile Compounds in DHA-Enriched Fish Oil on Accerlerated Oxidative Storage." Journal of Food Science 68 (2003): 2169-2177.

Liu, J.,. Killilea,D.W., and. Ames, B.N.,. "Age-Associated Mitochondrial Oxidative Decay: Improvement of Carnitine Acetyltransferase Substrate-Binding Affinity and Activity in Brain by Feeding Old Rats Acetyl -L-Carnitine and/or R-a-Lipoic Acid." PNAS 99 (2002): 1876-1881. www.pnas.org.

Liu, J, , et al. "Memory Loss in Old Rats is Associated with Brain Mitochondrial Decay and RNA/DNA Oxidation: Partial Reversal by Feeding Acetyl-L-Carnitine and/or R-a-Lipoic Acid." PNAS 99 (2002): 2356-2361. www.pnas.org.

Majumder, G.C., and. Ghosh, A. Project Reports- Proteins of Shilajit. Comp.. Ghosal.S. Drug Research & Development Centre. 2002.

Mantzioris, E., et al. "Biochemical Effects of a Diet Containing Foods Enriched with N-3 Fatty Acids." American Society for Clinical Nutrition 72 (2000): 42-48.

Marrow, J.D., et al. "A Series of Prostaglandin F2-Like Compounds are Produced in vivo in Humans by a Non-Cyclooxygenase, Free Radical-Catalyzed Mechanism." Porc. Natl. Acad. Sci. USA 87 (1990): 9383-9387.

Muruganandam,A.V., and Ghosal, S. Determination of Pro-Oxidant Activity, If Any, of Shilajit and DBPs. Indian Herbs Research & Supply Co. Ltd. 2001. 1-9.

Nordoy, A. "Is There a Rational Use for N-3 Fatty Acids (Fish Oils) in Clinical Medicine?" Drugs 42 (1991): 331-342.

Pandey, H.C., and Tewari, L.C.,. "Latex of Euphorbia royleana Boiss. the Source of Gomutra Shilajit (Shilajatu)- an Ancient Miraculous Drug of India." Quart. J. Crude Drug Res. 13 (1975): 135-142.

Phillips, Paul. "Unearthing the Evidence." Chemistry in Britain 33(1997): 32-34.

Pope, G.S. "Isolation of Two Benzocoumarins From "Clover Stone," a Type of Renal Calculus Found in Sheep." Ts.Biochemical Journal. 93(1964):474.

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Schectman, G, Kaul, S., and. Kissebah, A.H.,. "Heterogeneity of Low Density Lipoprotein Responses to Fish-Oil Supplementation in Hypertriglyceridemic Subjects." Arteriosclerosis 9 (1989): 345-354.

Schepetkin, I, Khlebnikov, A., and Kwon, B.S.,. "Medical Drugs From Humus Matter: Focus on Mumie." Drug Development Research 57 (2002): 140-159.

Singh, B. Monograph: Purified Shilajit Extract. Comp. De J. and Ghosal, S. Indian Herbs Research & Supply Co. Ltd. 2004. 1-7.

Singleton, C.B., Walker, B.D. and Campbell, T.J. "N-3 Polyunsaturated Fatty Acids and Cardiac Mortality." Aust NZ J Med 30 (2000): 246-251.

Starratt, A.N., and White, G.A. "Identification of Some Metabolites of Alternaria cucumerina (E.&E.) Ell." Phytochemistry 7 (1968): 1883-1884.

Steele, T. D.,. McCann,U.D., and. Ricaurte, G.A.. "3,4- Methylenedioxymethamphetamine (MDMA, "Ecstasy") : Pharmacology and Toxicology in Animals and Humans." Addiction 89 (1994): 539-551.

Storlien, LH., et al. "Diet Composition and Insulin Action in Animal Models." British Journal of Nutrition 83 (2000): 85-90.

Wilt, T J. , et al. "Fish Oil Supplementation Does Not Lower Plasma Cholesterol in Men with Hypercholesterolemia." Annals of Internal Medicine 111 (1989): 900-905.